diff --git a/build-scripts/config_common.cmake b/build-scripts/config_common.cmake
index f5a49c87..19f0772c 100644
--- a/build-scripts/config_common.cmake
+++ b/build-scripts/config_common.cmake
@@ -392,3 +392,7 @@ if (WAMR_BUILD_STATIC_PGO EQUAL 1)
   add_definitions (-DWASM_ENABLE_STATIC_PGO=1)
   message ("     AOT static PGO enabled")
 endif ()
+if (WAMR_DISABLE_WRITE_GS_BASE EQUAL 1)
+  add_definitions (-DWASM_DISABLE_WRITE_GS_BASE=1)
+  message ("     Write linear memory base addr to x86 GS register disabled")
+endif ()
diff --git a/core/config.h b/core/config.h
index 82e181f6..2c382d17 100644
--- a/core/config.h
+++ b/core/config.h
@@ -449,4 +449,11 @@
 #define WASM_ENABLE_STATIC_PGO 0
 #endif
 
+/* Disable writing linear memory base address to GS segment register,
+   by default only in linux x86-64, linear memory base addr is written
+   to GS segment register before calling wasm/aot function. */
+#ifndef WASM_DISABLE_WRITE_GS_BASE
+#define WASM_DISABLE_WRITE_GS_BASE 0
+#endif
+
 #endif /* end of _CONFIG_H_ */
diff --git a/core/shared/platform/linux/platform_internal.h b/core/shared/platform/linux/platform_internal.h
index 334808e5..8439f872 100644
--- a/core/shared/platform/linux/platform_internal.h
+++ b/core/shared/platform/linux/platform_internal.h
@@ -63,6 +63,7 @@ typedef sem_t korp_sem;
 
 #define bh_socket_t int
 
+#if WASM_DISABLE_WRITE_GS_BASE == 0
 #if defined(BUILD_TARGET_X86_64) || defined(BUILD_TARGET_AMD_64)
 #define os_writegsbase(base_addr)                                 \
     do {                                                          \
@@ -76,6 +77,7 @@ typedef sem_t korp_sem;
     _writegsbase_u64(((uint64)(uintptr_t)base_addr))
 #endif
 #endif
+#endif
 
 #if WASM_DISABLE_HW_BOUND_CHECK == 0
 #if defined(BUILD_TARGET_X86_64) || defined(BUILD_TARGET_AMD_64)            \
diff --git a/doc/build_wamr.md b/doc/build_wamr.md
index 4af3b73a..a9d33716 100644
--- a/doc/build_wamr.md
+++ b/doc/build_wamr.md
@@ -98,7 +98,7 @@ cmake -DWAMR_BUILD_PLATFORM=linux -DWAMR_BUILD_TARGET=ARM
 
 #### **Disable boundary check with hardware trap**
 - **WAMR_DISABLE_HW_BOUND_CHECK**=1/0, default to enable if not set and supported by platform
-> Note: by default only platform [linux/darwin/android/windows/vxworks 64-bit](https://github.com/bytecodealliance/wasm-micro-runtime/blob/5fb5119239220b0803e7045ca49b0a29fe65e70e/core/shared/platform/linux/platform_internal.h#L81) will enable the boundary check with hardware trap feature, for 32-bit platforms it's automatically disabled even when the flag set to 0, and the wamrc tool will generate AOT code without boundary check instructions in all 64-bit targets except SGX to improve performance. The boundary check includes linear memory access boundary and native stack access boundary, if `WAMR_DISABLE_STACK_HW_BOUND_CHECK` below isn't set.
+> Note: by default only platform [linux/darwin/android/windows/vxworks 64-bit](https://github.com/bytecodealliance/wasm-micro-runtime/blob/5fb5119239220b0803e7045ca49b0a29fe65e70e/core/shared/platform/linux/platform_internal.h#L81) will enable the boundary check with hardware trap feature, for 32-bit platforms it's automatically disabled even when the flag is set to 0, and the wamrc tool will generate AOT code without boundary check instructions in all 64-bit targets except SGX to improve performance. The boundary check includes linear memory access boundary and native stack access boundary, if `WAMR_DISABLE_STACK_HW_BOUND_CHECK` below isn't set.
 
 #### **Disable native stack boundary check with hardware trap**
 - **WAMR_DISABLE_STACK_HW_BOUND_CHECK**=1/0, default to enable if not set and supported by platform, same as `WAMR_DISABLE_HW_BOUND_CHECK`.
@@ -198,6 +198,13 @@ Currently we only profile the memory consumption of module, module_instance and
 - **WAMR_BUILD_STACK_GUARD_SIZE**=n, default to N/A if not set.
 > Note: By default, the stack guard size is 1K (1024) or 24K (if uvwasi enabled).
 
+### **Disable the writing linear memory base address to x86 GS segment register
+- **WAMR_DISABLE_WRITE_GS_BASE**=1/0, default to enable if not set and supported by platform
+> Note: by default only platform [linux x86-64](https://github.com/bytecodealliance/wasm-micro-runtime/blob/5fb5119239220b0803e7045ca49b0a29fe65e70e/core/shared/platform/linux/platform_internal.h#L67) will enable this feature, for 32-bit platforms it's automatically disabled even when the flag is set to 0. In linux x86-64, writing the linear memory base address to x86 GS segment register may be used to speedup the linear memory access for LLVM AOT/JIT, when `--enable-segue=[<flags>]` option is added for `wamrc` or `iwasm`.
+
+### **Enable running PGO(Profile-Guided Optimization) instrumented AOT file**
+- **WAMR_BUILD_STATIC_PGO**=1/0, default to disable if not set
+
 **Combination of configurations:**
 
 We can combine the configurations. For example, if we want to disable interpreter, enable AOT and WASI, we can run command: